17. Ibid.

18. Feinendegen, L. E. “Evidence for Beneficial Low Level Radiation Effects and Radiation Hormesis.” The British Journal of Radiology 78, no. 925 (2005): 3–7.

19. Ibid.

20. Miller, R. A., et al. “Big Mice Die Young: Early Life Body Weight Predicts Longevity in Genetically Heterogeneous Mice.” Aging Cell no. 1 (2002): 22–29.

21. He, Q., et al. “Shorter Men Live Longer: Association of Height with Longevity and FOXO3 Genotype in American Men of Japanese Ancestry.” PLoS One 9, no. 5 (2014): e94385.

22. Blagosklonny, M. V. “Big Mice Die Young but Large Animals Live Longer.” Aging (Albany, NY) 5, no. 4 (2013): 227–233.

Глава 2

1. Masoro, E. J. “Overview of Caloric Restriction and Ageing.” Mechanisms of Ageing Development 126, no. 9 (2005): 913–922.

2. McCay, C. M., et al. “The Effect of Retarded Growth upon the Length of Life Span and upon the Ultimate Body Size.” The Journal of Nutrition 10, no. 1 (1935): 63–79.

3. Richardson, A., et al. “Significant Life Extension by Ten Percent Dietary Restriction.” Annals of the New York Academy of Science 1363 (2016): 11–17.

4. Tannenbaum, A. “The Genesis and Growth of Tumors II. Effect of Caloric Restriction Per Se.” Cancer Research 2, no. 7 (1942): 460–467.

5. Carlson, A. J., and F. Hoelzel. “Apparent Prolongation of the Life Span of Rats by Intermittent Fasting.” Journal of Nutrition 31 (1946): 363–375.

6. Ross, M. H. “Protein, Calories and Life Expectancy.” Federation Proceedings 18 (1959): 1190–1207.

7. Iwasaki, K., et al. “The Influence of Dietary Protein Source on Longevity and Age-Related Disease Processes of Fischer Rats.” Journal of Gerontology 43, no. 1 (1988): B5–12.

8. Redman, L. M., and E. Ravussin. “Caloric Restriction in Humans: Impact on Physiological, Psychological, and Behavioral Outcomes.” Antioxidants & Redox Signaling 14, no. 2 (2011): 275–287; Suzuki, M., B. J. Wilcox, and C. D. Wilcox. “Implications from and for Food Cultures for Cardiovascular Disease: Longevity.” Asia Pacific Journal of Clinical Nutrition 10, no. 2 (2001): 165–171.

9. Stanfel, M. N., et al. “The TOR Pathway Comes of Age.” Biochimica et Biophysica Acta 1790, no. 10 (2009): 1067–1074.

10. McDonald, R. B., and J. J. Ramsey. “Honoring Clive McCay and 75 Years of Calorie Restriction Research.” Journal of Nutrition 140, no. 7 (2010): 1205–1210.

11. Bluher, M. “Fat Tissue and Long Life.” Obesity Facts 1, no. 4 (2008): 176–182.

12. Adelman, R., R. L. Saul, and B. N. Ames. “Oxidative Damage to DNA: Relation to Species Metabolic Rate and Life Span.” Proceedings of the National Academy of Sciences of the United States of America 85, no. 8 (1988): 2706–2708.

13. Hulbert, A. J., et al. “Life and Death: Metabolic Rate, Membrane Composition, and Life Span of Animals.” Physiological Reviews 87, no. 4 (2007): 1175–1213.

14. Mariotti, S., et al. “Complex Alteration of Thyroid Function in Healthy Centenarians.” Journal of Clinical Endocrinology and Metabolism 77, no. 5 (1993): 1130–1134.

15. См. примечание 1 выше.

16. Paolisso, G., et al. “Body Composition, Body Fat Distribution, and Resting Metabolic Rate in Healthy Centenarians.” American Journal of Clinical Nutrition 62, no. 4 (1995): 746–750.

17. Lee, S. J., C. T. Murphy, and C. Kenyon. “Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression.” Cell Metabolism 10, no. 5 (2009): 379–391.

18. Masoro, E. J., et al. “Dietary Restriction Alters Characteristics of Glucose Fuel Use.” Journal of Gerontology 47, no. 6 (1992): B202–208.

19. Kenyon, C., et al. “A C. elegans Mutant That Lives Twice as Long as Wild Type.” Nature366, no. 6454 (1993): 461–464.

20. “Cynthia Kenyon.” https://en.wikipedia.org/wiki/Cynthia_Kenyon.

21. Taubes, G. “Rare Form of Dwarfism Protects Against Cancer.” Discover, March 27, 2013. Открыто по адресу http://discovermagazine.com/2013/april/19-double-edged-genes.

22. Blagosklonny, M. V. “Calorie Restriction: Decelerating mTOR-Driven Aging from Cells to Organisms (Including Humans).” Cell Cycle 9, no. 4 (2010): 683–688.

23. Cuervo, A. M., et al. “Autophagy and Aging: The Importance of Maintaining ‘Clean’ Cells.” Autophagy 1, no. 3 (2005): 131–140.

24. Jia, K., and B. Levine. “Autophagy Is Required for Dietary Restriction-Mediated Life Span Extension in C. elegans.” Autophagy 3, no. 6 (2007): 597–599; Melendez, A., et al. “Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans.” Science 301, no. 5638 (2003): 1387–1391.

25. Alvers, A. L., et al. “Autophagy Is Required for Extension of Yeast Chronological Life Span by Rapamycin.” Autophagy 5, no. 6 (2009): 847–849.

26. Hardie, D. G., F. A. Ross, and S. A. Hawley. “AMPK: A Nutrient and Energy Sensor That Maintains Energy Homeostasis.” Nature Reviews Molecular Cell Biology 13, no. 4 (2012): 251–262.

27. Canto, C., and J. Auwerx. “Calorie Restriction: Is AMPK a Key Sensor and Effector?” Physiology (Bethesda) 26, no. 4 (2011): 214–224.

28. Lyons, C., and H. Roche. “Nutritional Modulation of AMPK-Impact upon Metabolic-Inflammation.” International Journal of Molecular Sciences 19, no. 10 (2018): 3092.

29. Anson, R. M., B. Jones, and R. de Cabod. “The Diet Restriction Paradigm: A Brief Review of the Effects of Every-Other-Day Feeding.” Age (Dordr) 27, no. 1 (2005): 17–25.

30. Hambly, C., et al. “Repletion of TNF-alpha or Leptin in Calorically Restricted Mice Suppresses Post-Restriction Hyperphagia.” Disease Model Mechanisms 5, no. 1 (2012): 83–94.

31. Goodrick, C. L., et al. “Effects of Intermittent Feeding upon Growth and Life Span in Rats.” Gerontology 28, no. 4 (1982): 233–241.

32. Goldberg, E. L., et al. “Lifespan-Extending Caloric Restriction or mTOR Inhibition Impair Adaptive Immunity of Old Mice by Distinct Mechanisms.” Aging Cell 14, no. 1 (2015): 130–138.

33. Ingram, D. K., et al. “Calorie Restriction Mimetics: An Emerging Research Field.” Aging Cell 5, no. 2 (2006): 97–108.

Глава 3

1. “Did a Canadian Medical Expedition Lead to the Discovery of an Anti-Aging Pill?” Bloomberg News, February 12, 2015. Открыто по адресу https://business.financialpost.com/news/did-a-canadian-medical-expedition-lead-to-the-discovery-of-an-anti-aging-pill.

2. Mohsin, N., et al. “Complete Regression of Visceral Kaposi’s Sarcoma After Conversion to Sirolimus.” Experimental and Clinical Transplantation 3, no. 2 (2005): 366–369.