and incidence of type 2 diabetes: a systematic review and meta-analysis. Int J Endocrinol. Epub 8. September 2013.

170 Norris, J. M. et al., Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes. JAMA 298 (12): 1420 – 1428, 2007.

171 Virtanen, J. K. et al., Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: The Kuopio Ischemic Heart Disease Risk Factor Study. Diabetes Care 37 (1): 189 – 196, 2014.

172 Ebbeling, C. B. et al., Effects of dietary composition on energy expenditure during weight-loss maintenance. JAMA 307 (24): 2627 – 2634, 2012.

173 Centers for Disease Control and Prevention, National Diabetes Statistics Report, 2014. Siehe http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf. Abgerufen 21. Juni 2018.

174 Worm, Nicolai, Flexi Carb, München: Riva Verlag 2016.

175 Seit einigen Jahren verwende ich zur soliden Diagnosesicherung zusätzlich das Instrument des Fatty-Liver-Index (FLI), ein Messwert der sich mit Hilfe einfacher Laborwerte aus dem Leberwert GGT in U/l, dem Triglyceridspiegel in mg/dl, dem Body-Mass-Index (BMI) sowie dem Bauchumfang berechnet. Im Internet zum Beispiel über die Webseite www.fegato.it können Sie unter FLI–Calculator den Index errechnen. Ein FLI > 60 macht das Vorliegen einer Fettleber sehr wahrscheinlich (zu 78 %). Falls Sie sich umfassender mit dem Thema beschäftigen wollen, kann ich Ihnen an dieser Stelle das Buch Schlank und gesund mit der Doc Fleck Methode, Hilden: BJV Verlag 2017 empfehlen, in dem ich diese Thematik sehr ausführlich beschreibe.

176 Hootman, J. M. et al., Updated Projected Prevalence of Self-Reported Doctor-Diagnosed Arthritis and Arthritis-Attributable Activity Limitation Among US Adults, 2015 – 2040. Arthritis&Rheumatology 68 (7): 1582 – 1587, 2016.

177 Ruskin, D. N. et al., Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet. PLoS ONE 4 (12): e8349, 2009.

178 Di Giuseppe, D. et al., Fish consumption and risk of rheumatoid arthritis: a dose-response meta-analysis. Arthritis Res Ther 16 (5): 446, 2014.

179 Lee, Y. H. et al., Omega-3 polyunsaturated fatty acids and the treatment of rheumatoid arthritis: a meta-analysis. Arch Med Res 43 (5): 356 – 62, 2012.

180 Kia, Sanam/Choy, Ernet, Update on treatment guideline in Fibromyalgia syndrome with focus on pharmacology. Biomedicines 5 (2): 20, 2017.

181 Deutsche Schmerzgesellschaft, Definition, Pathophysiologie, Diagnostik und Therapie des Fibromyalgiesyndroms, S. 16. S3-Leitlinie, 2. Aktualisierung von 2017. Online (PDF), zuletzt abgerufen am 20. Mai 2018.

182 Deutsche Schmerzgesellschaft: Definition, Pathophysiologie, Diagnostik und Therapie des Fibromyalgiesyndroms., S. 14 f. S3-Leitlinie, 2. Aktualisierung von 2017. Online (PDF), zuletzt abgerufen am 20. Mai 2018.

183 Watkins, L. R. et al., Glia: Novel counter-regulators or opioid analgesia. Trends Neurosci 28 (12): 661 – 69, 2005; Craig, A. D., How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci 3 (8): 655 – 66, 2002.

184 Berrendero, F. et al., Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. J Neurosci 25 (5): 1103 – 12, 2005.

185 Mercola, Fat for fuel.

186 Ernst, A./Shelley-Tremblay, J., Non-ketogenic, low carbohydrate diet predicts lower affective distress, higher energy levels and decreased Fibromyalgia symptoms in middle-aged females with Fibromyalgia Syndrome as compared to the Western pattern diet. Journal of Musculoskeletal Pain 21 (4): 365 – 370, 2013.

187 Balbás, G. M. et al., Study on the use of omega-3 fatty acids as a therapeutic supplement in treatment of psoriasis. Clin Cosmet Investig Dermatol 4: 73 – 77, 2011.

188 Eriksen, B. B./Kare, D. L., Open trial of supplements of omega 3 and 6 fatty acids, vitamins and minerals in atopic dermatitis. J Dermatolog Treat 17 (2): 82 – 85, 2006.

189 Scott, D. W. et al., Effect of an omega-3/omega-6 fatty acid-containing commercial lamb and rice diet on pruritus in atopic dogs: results of a single-blinded study. Can J Vet Res 61 (2): 145 – 153, 1997.

190 Gieler, Uwe et al., Psychosomatische Aspekte bei Hauterkrankungen: Akne vulgaris. In: Psychosomatische Dermatologie; AWMF-Leitlinien-Register Nr. 013/024. Siehe https://www.awmf.org/uploads/tx_szleitlinien/013 – 024l_S1_Psychosomatische_Dermatologie_2018 – 05.pdf. Abgerufen August 2018.

191 Oschman, J. L. et al., The effects of grounding (earthing) on inflammation, the immune response, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases. J Inflamm Res 8: 83 – 96, 2015.

192 Cordain, L. et al., Acne vulgaris: a disease of Western civilization. Arch Dermatol 138 (12): 1584 – 90, 2003.

193 Smith, R. N. et al., A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. Am J Clin Nutr 86 (1): 107 – 15, 2007.

194 Kwon, H. H. et al., Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients: a randomized, controlled trial. Acta Derm Venereol 92 (3): 241 – 46, 2012.

195 Mahmood, S. N./Bowe, W. P., Diet and acne update: carbohydrates emerge as the main culprit. J Drugs Dermatol 13 (4): 428 – 435, 2014.

196 Howlader, N et al., SEER Cancer Statistics Review, 1975 – 2013. National Cancer Institute Bethesda, MD April 2016. http://seer.cancer.gov/Csr/1975_2013/. Abgerufen am August 2017.

197 Mercola, Fat for fule, S. 17.

198 McKenzie, Sheena, «Yoshinori Ohsumi wins Nobel Prize for Medical Research on Cells», CNN website, 3. Oktober 2016, siehe http://www.cnn.com/2016/10/03/health/nobel-prize-2016-physiology-medicineyoshinori-ohsumi/. Abgerufen September 2018.

199 Maurer, G. D. et al., Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. BMC Cancer 11: 315, 2011.

200 Fukui, M. et al., EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction. J Cell Biochem 114 (1): 192 – 203, 2013.

201 Chajès, V. et al., ω-3 and ω-6 Polyunsaturated fatty acid intakes and the risk of breast cancer in Mexican women: impact of obesity status. Cancer Epidemiol Biomarkers Prev 21 (2): 319 – 326, 2012; Kim, J. et al., Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study. BMC Cancer 9: 216, 2009; Simonsen, N. et al., Adipose tissue omega-3 and omega-6 fatty acid content and breast cancer in the EURAMIC study. European Community Multicenter Study on Antioxidants, Myocardial Infarction, and Breast Cancer. Am J Epidemiol 147 (4): 342 – 352, 1998.

202 Arem, H. et al., Omega-3 and omega-6 fatty acid intakes and endometrial