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2 T.A. Branch et al., Historical Catch Series for Antarctic and Pygmy Blue Whales, Report (SC/60/SH9) to the International Whaling Commission (2008).

3 J.R. Miller et al., “The Challenges of Plastinating a Blue Whale (Balaenoptera musculus) Heart,” Journal of Plastination 29, no. 2 (2017): 22–29.

4 Knut Schmidt-Nielsen, Animal Physiology (Cambridge: Cambridge University Press, 1983), 207.

5 Knut Schmidt-Nielsen, Scaling: Why Is Animal Size So Important? (Cambridge: Cambridge University Press, 1984), 139.

6 J.A. Goldbogen et al., “Extreme Bradycardia and Tachycardia in the World’s Largest Animal,” Proceedings of the National Academy of Sciences 116, no. 50 (December 2019): 25329–32.

7 R. Monahan-Earley, A.M. Dvorak, and W.C. Aird. “Evolutionary Origins of the Blood Vascular System and Endothelium,” Journal of Thrombosis and Haemostasis (June 2013): 46–66.

8 Xiaoya Ma et al., “An Exceptionally Preserved Arthropod Cardiovascular System from the Early Cambrian,” Nature Communications 5, no. 3560 (2014).

9 Gary Kreamer and Stewart Michels, “History of Horseshoe Crab Harvest on Delaware Bay,” in Biology and Conservation of Horseshoe Crabs, eds. John T. Tanacredi, Mark L. Botton, and David Smith (New York: Springer, 2009), 299–302.

10 Kreamer and Michels, “Horseshoe Crab,” 307–309.

11 Mark L. Botton et al., “Emerging Issues in Horseshoe Crab Conservation: A Perspective from the IUCN Species Specialist Group,” in Changing Global Perspectives on Horseshoe Crab Biology, Conservation and Management, eds. Ruth Herrold Carmichael et al. (New York: Springer, 2015), 377–378.

12 Thomas Zimmer, “Effects of Tetrodotoxin on the Mammalian Cardiovascular System,” Marine Drugs 8, no. 3 (2010): 741–762.

13 “Researchers Discover How Blood Vessels Protect the Brain during Infl ammation,” Medical Xpress. February 21, 2019, https://medicalxpress.com/news/2019–02-blood-vessels-brain-inflammation.html.

14 Stephen S. Dominy et al., “Porphyromonas gingivalis in Alzheimer’s Disease Brains: Evidence for Disease Causation and Treatment with Small-Molecule Inhibitors,” Science Advances 5, no. 1 (January 23, 2019), https://advances.sciencemag.org/content/5/1/eaau3333.

15 Dominy et al. “Porphyromonas gingivalis.”

16 Terence Hines, “Zombies and Tetrodotoxin,” Skeptical Inquirer 32, no. 3 (May/June 2008).

17 D.M. Bramble and D.R. Carrier, “Running and Breathing in Mammals,” Science 219, no. 4582 (January 21, 1983): 251–256.

18 F.B. Bang, “A Bacterial Disease of Limulus polyphemus,” Bulletin of the Johns Hopkins Hospital 98, no. 5 (May 1956): 325–351.

19 S.P. Kapur and A. Sen Gupta. “The Role of Amoebocytes in the Regeneration of Shell in the Land Pulmonate, Euplecta indica (Pfi effer),” Biological Bulletin 139, no. 3 (1970): 502–509.

20 Jack Levin, Peter A. Tomasulo, and Ronald. S. Oser, “Detection of Endotoxin in Human Blood and Demonstration of an Inhibitor,” Journal of Laboratory and Clinical Medicine 75, no. 6 (June 1, 1970): 903.

21 “Horseshoe Crab,” Atlantic States Marine Fisheries Commission. http://www.asmfc.org/species/horseshoe-crab.

22 Michael J. Millard et al., “Assessment and Management of North American Horseshoe Crab Populations, with Emphasis on a Multispecies Framework for Delaware Bay, U.S.A. Populations,” in Changing Global Perspectives on Horseshoe Crab Biology, Conservation and Management, eds. Ruth Herrold Carmichael et al. (New York: Springer, 2015), 416.

23 “Horseshoe Crab,” ASMFC.

24 A.D. Jose and D. Collison. “The Normal Range and Determinants of the Intrinsic Heart Rate in Man,” Cardiovascular Research 4, no. 2 (April 1970): 160–167.

25 Sarah Zhang, “The Last Days of the Blue-Blood Harvest,” Atlantic, May 9, 2018, https://www.theatlantic.com/science/archive/2018/05/blood-in-the-water/559229/.

26 Silke Hagner-Holler et al., “A Respiratory Hemocyanin from an Insect,” Proceedings of the National Academy of Sciences 101, no. 3 (January 20, 2004): 871–874.

27 Hagner-Holler et al., “Respiratory Hemocyanin.”

28 Günther Pass et al., “Phylogenetic Relationships of the Orders of Hexapoda: Contributions from the Circulatory Organs for a Morphological Data Matrix,” Arthropod Systematics and Phylogeny 64, no. 2 (2006): 165–203.

29 Reinhold Hustert et al., “A New Kind of Auxiliary Heart in Insects: Functional Morphology and Neuronal Control of the Accessory Pulsatile Organs of the Cricket Ovipositor,” Frontiers in Zoology 11, no. 43 (2014).

30 SPRINT MIND Investigators for the SPRINT Research Group, “Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial,” Journal of the American Medical Association 321, no. 6 (2019):553–561.

31 Karin K. Petersen et al., “Protection against High Intravascular Pressure in Giraffe Legs,” American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 305, no. 9 (November 1, 2013) R1021–30.

32 “Sea Squirt Pacemaker Gives New Insight into Evolution of the Human Heart,” Healthcare-in-Europe.com, https://healthcare-in-europe.com/en/news/sea-squirt-pacemaker-gives-new-insight-into-evolution-of-the-human-heart.html.

33 Salynn Boyles, “Heart Attacks in the Morning Are More Severe,” WebMD, April 27, 1001, https://www.webmd.com/heart-disease/news/20110427/heart-attacks-in-the-morning-are-more-severe#1.

34 “Cholesterol Levels Vary by Season, Get Worse in Colder Months,” American College of Cardiology, March 27, 2014, https://www.acc.org/about-acc/press-releases/2014/03/27/13/50/joshi-seasonal-cholesterol-pr.

35 Srinivasan Damodaran. “Inhibition of Ice Crystal Growth in Ice Cream Mix by Gelatin Hydrolysate,” Journal of Agricultural and Food Chemistry 55, no. 26 (November 29, 2007): 10918–23.

36 David Goodsell, “Molecule of the Month: Antifreeze Proteins,” PBD-101, Protein Data Bank, December 2009, https://pdb101.rcsb.org/motm/120.

37 James M. Wiebler et al., “Urea Hydrolysis by Gut Bacteria in a Hibernating Frog: Evidence for Urea-Nitrogen Recycling in Amphibia,” Proceedings of the Royal Society B: Biological Sciences 285, no. 1878 (May 16, 2018).

38 Jon P. Costanzo, Jason T. Irwin, and Richard E. Lee Jr., “Freezing Impairment of Male Reproductive Behaviors of the FreezeTolerant Wood Frog, Rana sylvatica,” Physiological Zoology 70, no. 2 (March – April 1997): 158–166.

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