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Séralini, G.-E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., … de Vendômois, J. S. (2012). RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005. https://www.sciencedirect.com/science/article/pii/S0278691512005637
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Does the Seralini Corn Study Fiasco Mark a Turning Point in the Debate Over GM Food? Sep 30, 2012, Jon Entine, Forbes. https://www.forbes.com/sites/jonentine/2012/09/30/does-the-seralini-corn-study-fiasco-mark-a-turning-point-in-the-debate-over-gm-food/?sh=687d7c87bfaa
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Le Comité de Recherche et d’Information Indépendantes sur le Génie Génétique. https://criigen.org/
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Study linking GM maize to cancer must be taken seriously by regulators. Trial suggesting a GM maize strain causes cancer has attracted a torrent of abuse, but it cannot be swept under the carpet. https://www.theguardian.com/environment/2012/sep/28/study-gm-maize-cancer.
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ГМО: Разоблачение разоблачающих / 03.07.2013.https://remedium.ru/pharmacy/gmo-razoblachenie-razoblachayushchikh/
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Séralini, G.-E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., … de Vendômois, J. S. (2012). RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005
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Séralini, G.-E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., … de Vendômois, J. S. (2012). RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005
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Suzuki H, Mohr U, Kimmerle G. Spontaneous endocrine tumors in Sprague-Dawley rats. J Cancer Res Clin Oncol. 1979 Oct;95(2):187–96. doi: 10.1007/BF00401012. PMID: 521452. https://pubmed.ncbi.nlm.nih.gov/521452/
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Séralini, G.-E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., … de Vendômois, J. S. (2012). RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005. https://www.sciencedirect.com/science/article/pii/S0278691512005637
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Séralini, G.-E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., … de Vendômois, J. S. (2012). RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005. https://www.sciencedirect.com/science/article/pii/S0278691512005637
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Séralini, G.-E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., … de Vendômois, J. S. (2012). RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005. https://www.sciencedirect.com/science/article/pii/S0278691512005637
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Altun, Mikael & Bergman, Esbjörn & Edström, Erik & Johnson, Hans & Ulfhake, Brun. (2008). Behavioral impairments of the aging rat. Physiology & behavior. 92. 911-23. 10.1016/j.physbeh.2007.06.017.
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Global Health Estimates: Life expectancy and leading causes of death and disability / GHE: Life expectancy and healthy life expectancy. https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/ghe-life-expectancy-and-healthy-life-expectancy
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Gilles-Eric Séralini et al. / Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide / Food and Chemical Toxicology, Volume 53, 2013, Pages 476–483, ISSN 0278–6915, https://doi.org/10.1016/j.fct.2012.11.007. https://www.sciencedirect.com/science/article/pii/S0278691512008149
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Séralini et al. study conclusions not supported by data, says EU risk assessment community / 28 November 2012. https://www.efsa.europa.eu/en/press/news/121128
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Gilles-Eric Séralini et al. / Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide / Food and Chemical Toxicology, Volume 53, 2013, Pages 476–483, ISSN 0278–6915, https://doi.org/10.1016/j.fct.2012.11.007. https://www.sciencedirect.com/science/article/pii/S0278691512008149
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Gilles-Eric Séralini et al. / Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide / Food and Chemical Toxicology, Volume 53, 2013, Pages 476–483, ISSN 0278–6915, https://doi.org/10.1016/j.fct.2012.11.007. https://www.sciencedirect.com/science/article/pii/S0278691512008149
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Gilles-Eric Séralini et al. / Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide / Food and Chemical Toxicology, Volume 53, 2013, Pages 476–483, ISSN 0278–6915, https://doi.org/10.1016/j.fct.2012.11.007. https://www.sciencedirect.com/science/article/pii/S0278691512008149
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ГМО увеличивает продолжительность жизни самцов крыс. https://scinquisitor.livejournal.com/25873.html
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Séralini et al. study conclusions not supported by data, says EU risk assessment community / 28 November 2012. https://www.efsa.europa.eu/en/press/news/121128. Gilles-Eric Séralini et al. / Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide / Food and Chemical Toxicology, Volume 53, 2013, Pages 476–483, ISSN 0278–6915, https://doi.org/10.1016/j.fct.2012.11.007. https://www.sciencedirect.com/science/article/pii/S0278691512008149
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Final review of the Séralini et al. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology / Published: 28 November 2012 / EFSA Journal 2012; 10(11):2986. https://www.efsa.europa.eu/en/efsajournal/pub/2986
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Выполняет функции иноагента.
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He Jiankui. The Southern University of Science and Technology in Shenzhen, China.
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Популярный в 90-х американский сериал, герой которого давно стал мемом. https://en.wikipedia.org/wiki/Walker,_Texas_Ranger.
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Хотя сам механизм впервые был замечен намного раньше. За историей открытия и развития технологии можно проследить в материале CRISPR TIMELINE, https://www.broadinstitute.org/what-broad/areas-focus/project-spotlight/crispr-timeline.
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Cas-белки бывают разные, их функции тоже. Мы в этой главе сосредоточимся только на Cas9.
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Importance of the PAM Sequence in CRISPR Experiments. https://www.synthego.com/guide/how-to-use-crispr/pam-sequence
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А тут уже немного юридической магии. Дело в том, что по законам одних стран отредактированные при помощи CRISPR организмы считаются ГМО, а по законам других, таких как страны ЕС, – нет (https://www.jic.ac.uk/news/a-crispr-picture-emerges-on-european-union-gmo-directive).
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Further development of CRISPR-Cas9. https://www.mpg.de/11824984/crispr-cas9-development
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Например, недавно в продаже появились вот такие помидоры: GABA-enriched tomato is first CRISPR-edited food to enter market. https://www.nature.com/articles/d41587–021–00026–2.
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