медицинской школе), – каждый из вас помог мне написать эту книгу, потому что от каждого я узнал что-то новое о психических заболеваниях и человеческой природе. Для меня было честью и привилегией быть вашим психиатром.

Спасибо тем, кто выразил готовность попробовать мои «методы метаболического лечения», и особенно тем, кто смог поделиться своими историями в этой книге или публично выступить вместе со мной на презентациях, по телевидению и на национальном радио.

Перед всеми, кому я так и не смог помочь, несмотря на все испробованные варианты лечения, я хочу извиниться от своего имени и от имени своей профессии. Именно вы научили меня задавать вопросы и ставить под сомнение свою работу и область психического здоровья в целом, а также отвергать неприемлемую парадигму. Вы вдохновили меня на бесконечные размышления о неврологии, физиологии и человеческой жизни, подтолкнули к поиску лучших ответов. Я очень надеюсь, что эта книга сможет положить им начало.

Примечания

Глава 1

1. Saloni Dattani, Hannah Ritchie, and Max Roser. “Mental Health.” OurWorldInData.org. https://ourworld indata.org/mental-health. Retrieved 10/15/2021.

2. R. C. Kessler, P. Berglund, O. Demler, R. Jin, K. R. Merikangas, and E. E. Walters. “Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication.” Arch Gen Psychiatry 62(6) (2005): 593–602.

3. W. Wurm, K. Vogel, A. Holl, C. Ebner, D. Bayer, et al. “Depression-Burnout Overlap in Physicians.” PLOS ONE 11(3): e0149913 (2016). doi: 10.1371/journal.pone.0149913.

4. Ben Wigert and Sangeeta Agrawal. “Employee Burnout, Part 1: The 5 Main Causes.” Gallup. https://www.gallup.com/workplace/237059/employee-burnout-part-main-causes. aspx. Retrieved 5/28/19.

5. B. Bandelow and S. Michaelis. “Epidemiology of Anxiety Disorders in the 21st Century.” Dialogues Clin Neurosci 17(3) (2015): 327–335. doi: 10.31887/DCNS.2015.17.3/bbandelow.

6. R. D. Goodwin, A. H. Weinberger, J. H. Kim, M. Wu, and S. Galea. “Trends in Anxiety Among Adults in the United States, 2008–2018: Rapid Increases Among Young Adults.” J Psychiatr Res. 130 (2020): 441–446.doi: 10.1016/j.jpsychires.2020.08.014.

7. SAMHSA. “National Survey on Drug Use and Health: Comparison of 2008–2009 and 2016–2017 Population Percentages (50 States and the District of Columbia).” Substance Abuse and Mental Health Services Administration, US Department of Health and Human Services. https://www.samhsa.gov/data/ sites/default/files/cbhsq-reports/NSDUHsaeTrendTabs2017/NSDUHsaeLongTermCHG2017.pdf.

8. CDC. “Data & Statistics on Autism Spectrum Disorder.” Centers for Disease Control and Prevention, US Department of Health and Human Services. https://www.cdc.gov/ncbddd/autism/data.html. Retrieved 5/27/19.

9. S. H. Yutzy, C. R. Woofter, C. C. Abbott, I. M. Melhem, and B. S. Parish. “The Increasing Frequency of Mania and Bipolar Disorder: Causes and Potential Negative Impacts.” J Nerv Ment Dis. 200(5) (2012): 380–387. doi: 10.1097/NMD.0b013e3182531f17.

10. M. É. Czeisler, R. I. Lane, E. Petrosky, et al. “Mental Health, Substance Use, and Suicidal Ideation During the COVID-19 Pandemic – United States, June 24–30, 2020.” MMWR Morb Mortal Wkly Rep 69 (2020): 1049–1057. doi: 10.15585/mmwr.mm6932a1external icon.

11. The Lancet Global Health. “Mental Health Matters.” Lancet Glob Health 8(11) (November 2020): e1352.

12. Global Burden of Disease Collaborative Network. “Global Burden of Disease Study 2015 (GBD 2015) Life Expectancy, All-Cause and Cause-Specific Mortality 1980–2015.” Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2016.

13. US Department of Housing and Urban Development. “The 2010 Annual Homeless Assessment Report to Congress.” US Department of Housing and Urban Development. https://www.huduser.gov/portal/sites/ default/files/pdf/2010HomelessAssessmentReport.pdf.

14. Doris J. James and Lauren E. Glaze. “Mental Health Problems of Prison and Jail Inmates.” Bureau of Justice Statistics, US Dept. of Justice (September 2006). https://bjs.ojp.gov/library/publications/mental-health – problems-prison-and-jail-inmates.

15. National Institute of Mental Health. “Major Depression.” National Institute of Mental Health, US Dept.of Health and Human Services. https://www.nimh.nih.gov/health/statistics/major-depression#:~:text =all%20U.S.%20adults.-,Treatment%20of%20Major%20Depressive%20Episode%20Among%20Adults, treatment%20in%20the%20past%20year. Retrieved 2/18/2022.

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17. Sidney Zisook, Gary R. Johnson, Ilanit Tal, Paul Hicks, Peijun Chen, Lori Davis, Michael Thase, Yinjun Zhao, Julia Vertrees, and Somaia Mohamed. “General Predictors and Moderators of Depression Remission: A VAST-D Report.” Am. J Psychiatry 176(5) (May 1, 2019): 348–357. doi: 10.1176/appi.ajp.2018.18091079.

18. Diego Novick, Josep Maria Haro, David Suarez, Eduard Vieta, and Dieter Naber. “Recovery in the Outpatient Setting: 36-Month Results from the Schizophrenia Outpatients Health Outcomes (SOHO) Study.” Schizophr Res 108(1) (2009): 223–230. doi: 10.1016/j.schres.2008.11.007.

19. Adam Rogers. “Star Neuroscientist Tom Insel Leaves the Google-Spawned Verily for. . a Startup?” Wired. May 11, 2017. https://www.wired.com/2017/05/star-neuroscientist-tom-insel-leaves-google-spawned-verily-startup/#:~:text=%E2%80%9CI%20spent%2013%20years%20at,we%20moved%20the%20needle%20in.

Глава 2

1. G. L. Engel. “The Need for a New Medical Model: A Challenge for Biomedicine.” Science 196(4286) (1977): 129–136. doi: 10.1126/science.847460.

2. M. B. Howren, D. M. Lamkin, and J. Suls. “Associations of Depression with C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis.” Psychosom Med. 71(2) (February 2009): 171–186. doi: 10.1097/ PSY.0b013e3181907c1b.

3. E. Setiawan, S. Attwells, A. A. Wilson, R. Mizrahi, P. M. Rusjan, L. Miler, C. Xu, S. Sharma, S. Kish, S. Houle, and J. H. Meyer. “Association of Translocator Protein Total Distribution Volume with Duration of Untreated Major Depressive Disorder: A Cross-Sectional Study.” Lancet Psychiatry 5(4) (April 2018): 339–347. doi: 10.1016/S2215-0366(18)30048-8.

4. C. Zhuo, G. Li, X. Lin, et al. “The Rise and Fall of MRI Studies in Major Depressive Disorder.” Transl Psychiatry 9(335) (2019). doi.org/10.1038/s41398-019-0680-6.

5. A. L. Komaroff. “The Microbiome and Risk for Obesity and Diabetes.” JAMA 317(4) (2017): 355–356.doi: 10.1001/jama.2016.20099; K. E. Bouter, D. H. van Raalte, A. K. Groen, et al. “Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction.” Gastroenterology 152(7) (May 2017): 1671–1678. doi: 10.1053/j.gastro.2016.12.048; E. A. Mayer, K. Tillisch, and A. Gupta. “Gut/ Brain Axis and the Microbiota.” J Clin Invest 125(3) (2015): 926–938. doi: 10.1172/JCI76304.

6. J. A. Foster and K. A. McVey Neufeld. “Gut-Brain Axis: How the Microbiome Influences Anxiety and Depression.” Trends Neurosci 36(5) (May 2013): 305–312. doi: 10.1016/j.tins.2013.01.005.

Глава 3

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR. 4th ed. Arlington, VA: American Psychiatric Association, 2000: